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The Na(+)/H(+) exchanger contributes to increased smooth muscle proliferation and migration in a rat model of pulmonary arterial hypertension

Increased muscularity of small pulmonary vessels, involving enhanced proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs), is a key component of the vascular remodeling underlying the development of pulmonary hypertension (PH). Stimuli such as growth factors and hypoxia ind...

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Detalles Bibliográficos
Autores principales: Huetsch, John C., Jiang, Haiyang, Larrain, Carolina, Shimoda, Larissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823603/
https://www.ncbi.nlm.nih.gov/pubmed/26997630
http://dx.doi.org/10.14814/phy2.12729