Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer

Approximately 20% of breast cancer cases are human epidermal growth factor receptor 2 (HER2)-positive. This type of breast cancer is more aggressive and tends to reoccur more often than HER2-negative breast cancer. In this study, we synthesized trastuzumab (TZ)-grafted dendrimers to improve delivery...

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Detalles Bibliográficos
Autores principales: Kulhari, Hitesh, Pooja, Deep, Shrivastava, Shweta, Kuncha, Madhusudana, Naidu, V. G. M., Bansal, Vipul, Sistla, Ramakrishna, Adams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823704/
https://www.ncbi.nlm.nih.gov/pubmed/27052896
http://dx.doi.org/10.1038/srep23179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823704/
https://www.ncbi.nlm.nih.gov/pubmed/27052896
http://dx.doi.org/10.1038/srep23179

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