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PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway

Promoting endothelial cell (EC) migration is important not only for therapeutic angiogenesis, but also for accelerating re-endothelialization after vessel injury. Several recent studies have shown that inhibition of protein tyrosine phosphatase 1B (PTP1B) may promote EC migration and angiogenesis by...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Yan, Feng, Ye, Qing, Wu, Xiao, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823726/
https://www.ncbi.nlm.nih.gov/pubmed/27052191
http://dx.doi.org/10.1038/srep24111