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Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

In eukaryotes, genomic DNA is compacted as chromatin, in which histones and DNA form the nucleosome as the basic unit. DMC1 and RAD51 are essential eukaryotic recombinases that mediate homologous chromosome pairing during homologous recombination. However, the means by which these two recombinases d...

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Detalles Bibliográficos
Autores principales: Kobayashi, Wataru, Takaku, Motoki, Machida, Shinichi, Tachiwana, Hiroaki, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823753/
https://www.ncbi.nlm.nih.gov/pubmed/27052786
http://dx.doi.org/10.1038/srep24228