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Generation of KCL013 research grade human embryonic stem cell line carrying a mutation in the HTT gene

The KCL013 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (42 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plate...

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Detalles Bibliográficos
Autores principales: Jacquet, Laureen, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Stephenson, Emma, Ilic, Dusko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823765/
https://www.ncbi.nlm.nih.gov/pubmed/27345987
http://dx.doi.org/10.1016/j.scr.2016.01.011