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Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity

Recent large-scale genome analyses of human tissue samples have uncovered a high degree of genetic alterations and tumour heterogeneity in most tumour entities, independent of morphological phenotypes and histopathological characteristics. Assessment of genetic copy-number variation (CNV) and tumour...

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Detalles Bibliográficos
Autores principales: Zhong, Qing, Rüschoff, Jan H., Guo, Tiannan, Gabrani, Maria, Schüffler, Peter J., Rechsteiner, Markus, Liu, Yansheng, Fuchs, Thomas J., Rupp, Niels J., Fankhauser, Christian, Buhmann, Joachim M., Perner, Sven, Poyet, Cédric, Blattner, Miriam, Soldini, Davide, Moch, Holger, Rubin, Mark A., Noske, Aurelia, Rüschoff, Josef, Haffner, Michael C., Jochum, Wolfram, Wild, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823793/
https://www.ncbi.nlm.nih.gov/pubmed/27052161
http://dx.doi.org/10.1038/srep24146