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Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity
Recent large-scale genome analyses of human tissue samples have uncovered a high degree of genetic alterations and tumour heterogeneity in most tumour entities, independent of morphological phenotypes and histopathological characteristics. Assessment of genetic copy-number variation (CNV) and tumour...
Autores principales: | Zhong, Qing, Rüschoff, Jan H., Guo, Tiannan, Gabrani, Maria, Schüffler, Peter J., Rechsteiner, Markus, Liu, Yansheng, Fuchs, Thomas J., Rupp, Niels J., Fankhauser, Christian, Buhmann, Joachim M., Perner, Sven, Poyet, Cédric, Blattner, Miriam, Soldini, Davide, Moch, Holger, Rubin, Mark A., Noske, Aurelia, Rüschoff, Josef, Haffner, Michael C., Jochum, Wolfram, Wild, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823793/ https://www.ncbi.nlm.nih.gov/pubmed/27052161 http://dx.doi.org/10.1038/srep24146 |
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