Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

Diffuse Intrinsic Pontine Gliomas (DIPGs) are deadly paediatric brain tumours where needle biopsies help guide diagnosis and targeted therapies. To address spatial heterogeneity, here we analyse 134 specimens from various neuroanatomical structures of whole autopsy brains from nine DIPG patients. Ev...

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Detalles Bibliográficos
Autores principales: Nikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G., Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I., Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L., Ellezam, Benjamin, Ingram, Wendy J., Stinson, Caedyn, Moore, Andrew S., Warren, Katherine E., Karamchandani, Jason, Packer, Roger J., Jabado, Nada, Majewski, Jacek, Nazarian, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823825/
https://www.ncbi.nlm.nih.gov/pubmed/27048880
http://dx.doi.org/10.1038/ncomms11185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823825/
https://www.ncbi.nlm.nih.gov/pubmed/27048880
http://dx.doi.org/10.1038/ncomms11185

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