Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

Senescent cells, formed in response to physiological and oncogenic stresses, facilitate protection from tumourigenesis and aid in tissue repair. However, accumulation of such cells in tissues contributes to age-related pathologies. Resistance of senescent cells to apoptotic stimuli may contribute to...

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Detalles Bibliográficos
Autores principales: Yosef, Reut, Pilpel, Noam, Tokarsky-Amiel, Ronit, Biran, Anat, Ovadya, Yossi, Cohen, Snir, Vadai, Ezra, Dassa, Liat, Shahar, Elisheva, Condiotti, Reba, Ben-Porath, Ittai, Krizhanovsky, Valery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823827/
https://www.ncbi.nlm.nih.gov/pubmed/27048913
http://dx.doi.org/10.1038/ncomms11190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823827/
https://www.ncbi.nlm.nih.gov/pubmed/27048913
http://dx.doi.org/10.1038/ncomms11190

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