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The combinatorial approach of laser-captured microdissection and reverse transcription quantitative polymerase chain reaction accurately determines HER2 status in breast cancer

BACKGROUND: HER2 expression in breast cancer correlates with increased metastatic potential, higher tumor recurrence rates and improved response to targeted therapies. Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) are two methods commonly used for the analysis of HER2 in t...

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Detalles Bibliográficos
Autores principales: Hofmann, Elisabeth, Seeboeck, Rita, Jacobi, Nico, Obrist, Peter, Huter, Samuel, Klein, Christian, Oender, Kamil, Wiesner, Christoph, Hundsberger, Harald, Eger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823853/
https://www.ncbi.nlm.nih.gov/pubmed/27057311
http://dx.doi.org/10.1186/s40364-016-0062-7