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B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus
BACKGROUND: Neuropsychiatric lupus (NPSLE) can be one of the earliest clinical manifestations in human lupus. However, its mechanisms are not fully understood. In lupus, a compromised blood-brain barrier may allow for the passage of circulating autoantibodies into the brain, where they can induce ne...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823887/ https://www.ncbi.nlm.nih.gov/pubmed/27055816 http://dx.doi.org/10.1186/s12974-016-0537-3 |