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ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells

Rho GTPase-activating proteins (RhoGAPs) are implicated in the development and progression of ovarian cancer. ARHGAP10 is a member of RhoGAP proteins and inactivates Cdc42 by converting GTP-bound form to GDP-bound form. Here, we aimed to evaluate ARHGAP10 expression profile and functions in ovarian...

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Detalles Bibliográficos
Autores principales: Luo, N, Guo, J, Chen, L, Yang, W, Qu, X, Cheng, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823924/
https://www.ncbi.nlm.nih.gov/pubmed/27010858
http://dx.doi.org/10.1038/cddis.2015.401