Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus

Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays important roles in cell maintenance, expansion and differentiation. Removal of genes essential for autophagy from embryonic neural stem and precursor cells reduces the survival and inhibits neuronal differentiation of...

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Detalles Bibliográficos
Autores principales: Xi, Y, Dhaliwal, J S, Ceizar, M, Vaculik, M, Kumar, K L, Lagace, D C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823925/
https://www.ncbi.nlm.nih.gov/pubmed/26938300
http://dx.doi.org/10.1038/cddis.2015.406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823925/
https://www.ncbi.nlm.nih.gov/pubmed/26938300
http://dx.doi.org/10.1038/cddis.2015.406

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