Cargando…

Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus

Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays important roles in cell maintenance, expansion and differentiation. Removal of genes essential for autophagy from embryonic neural stem and precursor cells reduces the survival and inhibits neuronal differentiation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xi, Y, Dhaliwal, J S, Ceizar, M, Vaculik, M, Kumar, K L, Lagace, D C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823925/ https://www.ncbi.nlm.nih.gov/pubmed/26938300 http://dx.doi.org/10.1038/cddis.2015.406

Ejemplares similares

Enhanced plasticity of mature granule cells reduces survival of newborn neurons in the adult mouse hippocampus
por: Kleine Borgmann, Felix B, et al.
Publicado: (2016)

CX3 chemokine receptor 1 deficiency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus
por: Xiao, Feng, et al.
Publicado: (2015)

Doublecortin (DCX) is not Essential for Survival and Differentiation of Newborn Neurons in the Adult Mouse Dentate Gyrus
por: Dhaliwal, Jagroop, et al.
Publicado: (2016)

Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
por: Kim, Myungjin, et al.
Publicado: (2016)

Short-Term, Voluntary Exercise Affects Morpho-Functional Maturation of Adult-Generated Neurons in Rat Hippocampus
por: Lattanzi, Davide, et al.
Publicado: (2022)

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
por: Avaliani, Natalia, et al.
Publicado: (2017)

A specific ATG-4 isoform is required for autophagic maturation and clearance in C. elegans neurons
por: Hill, Sarah E., et al.
Publicado: (2019)

Excitable Adult-Generated GABAergic Neurons Acquire Functional Innervation in the Cortex after Stroke
por: Kannangara, Timal S., et al.
Publicado: (2018)

Mature neurons: equipped for survival
por: Kole, A J, et al.
Publicado: (2013)

Swapping of interaction partners with ATG5 for autophagosome maturation
por: Kim, Jun Hoe, et al.
Publicado: (2015)

Functional Convergence of Neurons Generated in the Developing and Adult Hippocampus
por: Laplagne, Diego A, et al.
Publicado: (2006)

Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2
por: Dhaliwal, Jagroop, et al.
Publicado: (2018)

Reduced Cholinergic Activity in the Hippocampus of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein Knockout Mice
por: Madokoro, Yuta, et al.
Publicado: (2019)

Reduced exploratory behavior in neuronal nucleoredoxin knockout mice
por: Tran, Bao Ngoc, et al.
Publicado: (2021)

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
por: Song, Z-H, et al.
Publicado: (2015)

ATG4A regulates human erythroid maturation and mitochondrial clearance
por: Stolla, Massiel Chavez, et al.
Publicado: (2022)

Post-Stroke Environmental Enrichment Improves Neurogenesis and Cognitive Function and Reduces the Generation of Aberrant Neurons in the Mouse Hippocampus
por: Woitke, Florus, et al.
Publicado: (2023)

Erythropoietin Stimulates GABAergic Maturation in the Mouse Hippocampus
por: Khalid, Kasifa, et al.
Publicado: (2021)

ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1
por: Frangež, Živa, et al.
Publicado: (2021)

TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A
por: Sun, Yizhe, et al.
Publicado: (2017)

BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus
por: Bunk, E C, et al.
Publicado: (2010)

Neuronal seipin knockout facilitates Aβ-induced neuroinflammation and neurotoxicity via reduction of PPARγ in hippocampus of mouse
por: Qian, Yun, et al.
Publicado: (2016)

Acute gut inflammation reduces neural activity and spine maturity in hippocampus but not basolateral amygdala
por: Matisz, Chelsea E., et al.
Publicado: (2022)

Neuronal networks of the hippocampus /
por: Traub, Roger D.
Publicado: (1991)

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures
por: Kaiser, Stephen E., et al.
Publicado: (2012)

Peptidomic characterization of peptide processing in the hippocampus of Wfs1 knockout mice
por: Tein, Karin, et al.
Publicado: (2015)

Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus
por: Yagi, Shunya, et al.
Publicado: (2020)

COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampus
por: Bayat, Amir-Hossein, et al.
Publicado: (2022)

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2012)

Knockout of Arabidopsis Serotonin N-Acetyltransferase-2 Reduces Melatonin Levels and Delays Flowering
por: Lee, Hyoung Yool, et al.
Publicado: (2019)

ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells
por: Lee, JaeYung, et al.
Publicado: (2021)

ATG5 knockout promotes paclitaxel sensitivity in drug-resistant cells via induction of necrotic cell death
por: Hwang, Sung-Hee, et al.
Publicado: (2020)

KCC2 is required for the survival of mature neurons but not for their development
por: Kontou, Georgina, et al.
Publicado: (2021)

Different effects of Atg2 and Atg18 mutations on Atg8a and Atg9 trafficking during starvation in Drosophila()
por: Nagy, Péter, et al.
Publicado: (2014)

Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice
por: Tein, Karin, et al.
Publicado: (2015)

Pgrmc1 Knockout Impairs Oocyte Maturation in Zebrafish
por: Wu, Xin-Jun, et al.
Publicado: (2018)

Microglia and neurons in the hippocampus of migratory sandpipers
por: Diniz, C.G., et al.
Publicado: (2015)

Chronic Lorcaserin Treatment Reverses the Nicotine Withdrawal-Induced Disruptions to Behavior and Maturation in Developing Neurons in the Hippocampus of Rats
por: Zaniewska, Magdalena, et al.
Publicado: (2021)

Closing the loop: Three musketeers of autophagy-ATG2, ATG18a, and ATG9
por: Mishra, Divya
Publicado: (2023)

Neuroligin-1 knockdown reduces survival of adult-generated newborn hippocampal neurons
por: Schnell, Eric, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qal5nb9t829vn6laj65pi0e59m