Cargando…

Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation

A virus that reproduces in a host without killing cells can easily establish a successful infection. Previously, we showed that dengue-2, a virus that threatens 40% of the world, induces autophagy, enabling dengue to reproduce in cells without triggering cell death. Autophagy further protects the vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Datan, E, Roy, S G, Germain, G, Zali, N, McLean, J E, Golshan, G, Harbajan, S, Lockshin, R A, Zakeri, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823927/
https://www.ncbi.nlm.nih.gov/pubmed/26938301
http://dx.doi.org/10.1038/cddis.2015.409