Cargando…
Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation
A virus that reproduces in a host without killing cells can easily establish a successful infection. Previously, we showed that dengue-2, a virus that threatens 40% of the world, induces autophagy, enabling dengue to reproduce in cells without triggering cell death. Autophagy further protects the vi...
Autores principales: | Datan, E, Roy, S G, Germain, G, Zali, N, McLean, J E, Golshan, G, Harbajan, S, Lockshin, R A, Zakeri, Z |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823927/ https://www.ncbi.nlm.nih.gov/pubmed/26938301 http://dx.doi.org/10.1038/cddis.2015.409 |
Ejemplares similares
-
Zika virus triggers autophagy to exploit host lipid metabolism and drive viral replication
por: Stoyanova, Gloria, et al.
Publicado: (2023) -
Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both in vitro and in vivo
por: Lee, Ying-Ray, et al.
Publicado: (2018) -
PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis
por: Ji, Guang-rong, et al.
Publicado: (2015) -
The variability of autophagy and cell death susceptibility: Unanswered questions
por: Loos, Ben, et al.
Publicado: (2013) -
ER stress PERKs up an miRNA
por: Short, Ben
Publicado: (2012)