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MiR-125a-5p decreases after long non-coding RNA HOTAIR knockdown to promote cancer cell apoptosis by releasing caspase 2

HOTAIR (homeobox transcript antisense RNA), one of the prototypical long non-coding RNAs, has been verified overexpressed in multiple carcinomas and has emerged as a promising novel anticancer target. Its well-established role is acting as a predictor of poor prognosis and promoting cancer cell meta...

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Detalles Bibliográficos
Autores principales: Tang, L, Shen, H, Li, X, Li, Z, Liu, Z, Xu, J, Ma, S, Zhao, X, Bai, X, Li, M, Wang, Q, Ji, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823942/
https://www.ncbi.nlm.nih.gov/pubmed/26962687
http://dx.doi.org/10.1038/cddis.2016.41