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Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway

Podocyte apoptosis is a major mechanism that leads to proteinuria in many chronic kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. The Rho family of small GTPases has been shown to be required in maintaining podocyte st...

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Detalles Bibliográficos
Autores principales: Huang, Z, Zhang, L, Chen, Y, Zhang, H, Zhang, Q, Li, R, Ma, J, Li, Z, Yu, C, Lai, Y, Lin, T, Zhao, X, Zhang, B, Ye, Z, Liu, S, Wang, W, Liang, X, Liao, R, Shi, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823952/
https://www.ncbi.nlm.nih.gov/pubmed/26986510
http://dx.doi.org/10.1038/cddis.2016.51