NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism

Membrane-bound CD40L (mCD40L) but not soluble CD40L (sCD40L) has been implicated in direct cell death induction and apoptosis in CD40-expressing carcinomas. In this study, we show that mCD40L but not sCD40L induces NORE1A/Rassf5 expression in an NFκB-dependant mechanism. NORE1A expression appeared t...

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Detalles Bibliográficos
Autores principales: Elmetwali, T, Salman, A, Palmer, D H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823953/
https://www.ncbi.nlm.nih.gov/pubmed/26986513
http://dx.doi.org/10.1038/cddis.2016.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823953/
https://www.ncbi.nlm.nih.gov/pubmed/26986513
http://dx.doi.org/10.1038/cddis.2016.52

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