Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy

Studies on the role of Wnt/β-catenin signaling in different forms of kidney disease have yielded discrepant results. Here, we report the biphasic change of renal β-catenin expression in mice with overload proteinuria in which β-catenin was upregulated at the early stage (4 weeks after disease induct...

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Detalles Bibliográficos
Autores principales: Wong, D W L, Yiu, W H, Wu, H J, Li, R X, Liu, Y, Chan, K W, Leung, J C K, Chan, L Y Y, Lai, K N, Tang, S C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823961/
https://www.ncbi.nlm.nih.gov/pubmed/27010856
http://dx.doi.org/10.1038/cddis.2016.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823961/
https://www.ncbi.nlm.nih.gov/pubmed/27010856
http://dx.doi.org/10.1038/cddis.2016.62

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