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Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy
Studies on the role of Wnt/β-catenin signaling in different forms of kidney disease have yielded discrepant results. Here, we report the biphasic change of renal β-catenin expression in mice with overload proteinuria in which β-catenin was upregulated at the early stage (4 weeks after disease induct...
Autores principales: | Wong, D W L, Yiu, W H, Wu, H J, Li, R X, Liu, Y, Chan, K W, Leung, J C K, Chan, L Y Y, Lai, K N, Tang, S C W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823961/ https://www.ncbi.nlm.nih.gov/pubmed/27010856 http://dx.doi.org/10.1038/cddis.2016.62 |
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