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Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction

Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and polarity. Members of the Rho-related family of small GTPases and their interacting proteins play multiple roles in regulating epithelial morphog...

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Detalles Bibliográficos
Autores principales: Loebel, David A. F., Plageman, Timothy F., Tang, Theresa L., Jones, Vanessa J., Muccioli, Maria, Tam, Patrick P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823982/
https://www.ncbi.nlm.nih.gov/pubmed/26772200
http://dx.doi.org/10.1242/bio.014415