Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA

DPF3 (BAF45c) is a member of the BAF chromatin remodeling complex. Two isoforms have been described, namely DPF3a and DPF3b. The latter binds to acetylated and methylated lysine residues of histones. Here, we elaborate on the role of DPF3a and describe a novel pathway of cardiac gene transcription l...

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Detalles Bibliográficos
Autores principales: Cui, Huanhuan, Schlesinger, Jenny, Schoenhals, Sophia, Tönjes, Martje, Dunkel, Ilona, Meierhofer, David, Cano, Elena, Schulz, Kerstin, Berger, Michael F., Haack, Timm, Abdelilah-Seyfried, Salim, Bulyk, Martha L., Sauer, Sascha, Sperling, Silke R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824069/
https://www.ncbi.nlm.nih.gov/pubmed/26582913
http://dx.doi.org/10.1093/nar/gkv1244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824069/
https://www.ncbi.nlm.nih.gov/pubmed/26582913
http://dx.doi.org/10.1093/nar/gkv1244

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