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Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA
DPF3 (BAF45c) is a member of the BAF chromatin remodeling complex. Two isoforms have been described, namely DPF3a and DPF3b. The latter binds to acetylated and methylated lysine residues of histones. Here, we elaborate on the role of DPF3a and describe a novel pathway of cardiac gene transcription l...
Autores principales: | Cui, Huanhuan, Schlesinger, Jenny, Schoenhals, Sophia, Tönjes, Martje, Dunkel, Ilona, Meierhofer, David, Cano, Elena, Schulz, Kerstin, Berger, Michael F., Haack, Timm, Abdelilah-Seyfried, Salim, Bulyk, Martha L., Sauer, Sascha, Sperling, Silke R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824069/ https://www.ncbi.nlm.nih.gov/pubmed/26582913 http://dx.doi.org/10.1093/nar/gkv1244 |
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