Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements

A mechanism by which control DNA elements regulate transcription over large linear genomic distances is by achieving close physical proximity with genes, and looping of the intervening chromatin paths. Alterations of such regulatory ‘chromatin looping’ systems are likely to play a critical role in h...

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Detalles Bibliográficos
Autores principales: Moisan, Stéphanie, Berlivet, Soizik, Ka, Chandran, Gac, Gérald Le, Dostie, Josée, Férec, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824072/
https://www.ncbi.nlm.nih.gov/pubmed/26615198
http://dx.doi.org/10.1093/nar/gkv1300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824072/
https://www.ncbi.nlm.nih.gov/pubmed/26615198
http://dx.doi.org/10.1093/nar/gkv1300

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