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Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements
A mechanism by which control DNA elements regulate transcription over large linear genomic distances is by achieving close physical proximity with genes, and looping of the intervening chromatin paths. Alterations of such regulatory ‘chromatin looping’ systems are likely to play a critical role in h...
Autores principales: | Moisan, Stéphanie, Berlivet, Soizik, Ka, Chandran, Gac, Gérald Le, Dostie, Josée, Férec, Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824072/ https://www.ncbi.nlm.nih.gov/pubmed/26615198 http://dx.doi.org/10.1093/nar/gkv1300 |
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