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Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms

DNA double stranded breaks (DSBs) are one of the most deleterious types of DNA lesions. The main pathways responsible for repairing these breaks in eukaryotic cells are homologous recombination (HR) and non-homologous end-joining (NHEJ). However, a third group of still poorly characterized DSB repai...

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Detalles Bibliográficos
Autores principales: Kostyrko, Kaja, Mermod, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824085/
https://www.ncbi.nlm.nih.gov/pubmed/26657630
http://dx.doi.org/10.1093/nar/gkv1349