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Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin

The nuclear immunophilin FKBP25 interacts with chromatin-related proteins and transcription factors and is suggested to interact with nucleic acids. Currently the structural basis of nucleic acid binding by FKBP25 is unknown. Here we determined the nuclear magnetic resonance (NMR) solution structure...

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Detalles Bibliográficos
Autores principales: Prakash, Ajit, Shin, Joon, Rajan, Sreekanth, Yoon, Ho Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824100/
https://www.ncbi.nlm.nih.gov/pubmed/26762975
http://dx.doi.org/10.1093/nar/gkw001