RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever

Fever is commonly used to diagnose disease and is consistently associated with increased mortality in critically ill patients. However, the molecular controls of elevated body temperature are poorly understood. We discovered that the expression of RNA-binding motif protein 3 (RBM3), known to respond...

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Detalles Bibliográficos
Autores principales: Wong, Justin J.-L., Au, Amy Y.M., Gao, Dadi, Pinello, Natalia, Kwok, Chau-To, Thoeng, Annora, Lau, Katherine A., Gordon, Jane E.A., Schmitz, Ulf, Feng, Yue, Nguyen, Trung V., Middleton, Robert, Bailey, Charles G., Holst, Jeff, Rasko, John E.J., Ritchie, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824108/
https://www.ncbi.nlm.nih.gov/pubmed/26825461
http://dx.doi.org/10.1093/nar/gkw041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824108/
https://www.ncbi.nlm.nih.gov/pubmed/26825461
http://dx.doi.org/10.1093/nar/gkw041

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