Cargando…

The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation

The exosome plays an important role in RNA degradation and processing. In archaea, three Rrp41:Rrp42 heterodimers assemble into a barrel like structure that contains a narrow RNA entrance pore and a lumen that contains three active sites. Here, we demonstrate that this quaternary structure of the ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Audin, Maxime J. C., Wurm, Jan Philip, Cvetkovic, Milos A., Sprangers, Remco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824110/
https://www.ncbi.nlm.nih.gov/pubmed/26837575
http://dx.doi.org/10.1093/nar/gkw062