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Mechanism of DNA loading by the DNA repair helicase XPD

The xeroderma pigmentosum group D (XPD) helicase is a component of the transcription factor IIH complex in eukaryotes and plays an essential role in DNA repair in the nucleotide excision repair pathway. XPD is a 5′ to 3′ helicase with an essential iron–sulfur cluster. Structural and biochemical stud...

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Detalles Bibliográficos
Autores principales: Constantinescu-Aruxandei, Diana, Petrovic-Stojanovska, Biljana, Penedo, J. Carlos, White, Malcolm F., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824113/
https://www.ncbi.nlm.nih.gov/pubmed/26896802
http://dx.doi.org/10.1093/nar/gkw102