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Quantitative assessment of ribosome drop-off in E. coli

Premature ribosome drop-off is one of the major errors in translation of mRNA by ribosomes. However, repeated analyses of Ribo-seq data failed to quantify its strength in E. coli. Relying on a novel highly sensitive data analysis method we show that a significant rate of ribosome drop-off is measura...

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Detalles Bibliográficos
Autores principales: Sin, Celine, Chiarugi, Davide, Valleriani, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824120/
https://www.ncbi.nlm.nih.gov/pubmed/26935582
http://dx.doi.org/10.1093/nar/gkw137