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CASSIS and SMIPS: promoter-based prediction of secondary metabolite gene clusters in eukaryotic genomes

Motivation: Secondary metabolites (SM) are structurally diverse natural products of high pharmaceutical importance. Genes involved in their biosynthesis are often organized in clusters, i.e., are co-localized and co-expressed. In silico cluster prediction in eukaryotic genomes remains problematic ma...

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Detalles Bibliográficos
Autores principales: Wolf, Thomas, Shelest, Vladimir, Nath, Neetika, Shelest, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824125/
https://www.ncbi.nlm.nih.gov/pubmed/26656005
http://dx.doi.org/10.1093/bioinformatics/btv713