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CASSIS and SMIPS: promoter-based prediction of secondary metabolite gene clusters in eukaryotic genomes
Motivation: Secondary metabolites (SM) are structurally diverse natural products of high pharmaceutical importance. Genes involved in their biosynthesis are often organized in clusters, i.e., are co-localized and co-expressed. In silico cluster prediction in eukaryotic genomes remains problematic ma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824125/ https://www.ncbi.nlm.nih.gov/pubmed/26656005 http://dx.doi.org/10.1093/bioinformatics/btv713 |