Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Granzyme A, a serine protease expressed in the granules of cytotoxic T and Natural Killer cells, is involved in the generation of pro-inflammatory cytokines by macrophages. Granzyme A has been described to induce in macrophages in vitro the activation of pro-inflammatory pathways that impair intrace...

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Detalles Bibliográficos
Autores principales: Uranga, Santiago, Marinova, Dessislava, Martin, Carlos, Pardo, Julián, Aguilo, Nacho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824395/
https://www.ncbi.nlm.nih.gov/pubmed/27055232
http://dx.doi.org/10.1371/journal.pone.0153028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824395/
https://www.ncbi.nlm.nih.gov/pubmed/27055232
http://dx.doi.org/10.1371/journal.pone.0153028

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