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Recognition of the bacterial alarmone ZMP through long-distance association of two RNA sub-domains

The bacterial alarmone 5-aminoimidazole-4-carboxamide riboside 5'-triphosphate (ZTP), derived from the monophosphorylated purine precursor ZMP, accumulates during folate starvation. ZTP regulates genes involved in purine and folate metabolism through a cognate riboswitch. The linker connecting...

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Detalles Bibliográficos
Autores principales: Jones, Christopher P., Ferré-D’Amaré, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824399/
https://www.ncbi.nlm.nih.gov/pubmed/26280533
http://dx.doi.org/10.1038/nsmb.3073