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Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling

We used established databases in standard ways to systematically characterize gene ontologies, pathways and functional linkages in the large set of genes now associated with autism spectrum disorders (ASDs). These conditions are particularly challenging—they lack clear pathognomonic biological marke...

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Detalles Bibliográficos
Autores principales: Wen, Ya, Alshikho, Mohamad J., Herbert, Martha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824422/
https://www.ncbi.nlm.nih.gov/pubmed/27055244
http://dx.doi.org/10.1371/journal.pone.0153329