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A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts

O-linked glycosylation is an important post-translational modification of mucin-type protein, changes to which are important biomarkers of cancer. For this study of the enzymes of O-glycosylation, we developed a shorthand notation for representing GalNAc-linked oligosaccharides, a method for their g...

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Detalles Bibliográficos
Autores principales: McDonald, Andrew G., Tipton, Keith F., Davey, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824424/
https://www.ncbi.nlm.nih.gov/pubmed/27054587
http://dx.doi.org/10.1371/journal.pcbi.1004844