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Ovarian cancer treatment with a tumor-targeting and gene expression-controllable lipoplex

Overexpression of folate receptor alpha (FRα) and high telomerase activity are considered to be the characteristics of ovarian cancers. In this study, we developed FRα-targeted lipoplexes loaded with an hTERT promoter-regulated plasmid that encodes a matrix protein (MP) of the vesicular stomatitis v...

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Detalles Bibliográficos
Autores principales: He, Zhi-Yao, Deng, Feng, Wei, Xia-Wei, Ma, Cui-Cui, Luo, Min, Zhang, Ping, Sang, Ya-Xiong, Liang, Xiao, Liu, Li, Qin, Han-Xiao, Shen, Ya-Li, Liu, Ting, Liu, Yan-Tong, Wang, Wei, Wen, Yan-Jun, Zhao, Xia, Zhang, Xiao-Ning, Qian, Zhi-Yong, Wei, Yu-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824455/
https://www.ncbi.nlm.nih.gov/pubmed/27026065
http://dx.doi.org/10.1038/srep23764