Cargando…

Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response

Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Kai, Zhang, Meng, Zhang, Lei, Wang, Peng, Song, Guanhua, Liu, Bingyu, Wu, Haifeng, Yin, Zhinan, Gao, Chengjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824456/
https://www.ncbi.nlm.nih.gov/pubmed/27026194
http://dx.doi.org/10.1038/srep23771