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Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response
Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to...
Autores principales: | Zhao, Kai, Zhang, Meng, Zhang, Lei, Wang, Peng, Song, Guanhua, Liu, Bingyu, Wu, Haifeng, Yin, Zhinan, Gao, Chengjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824456/ https://www.ncbi.nlm.nih.gov/pubmed/27026194 http://dx.doi.org/10.1038/srep23771 |
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