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The PDZ Protein Na(+)/H(+) Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization

Directional flow of the cerebrospinal fluid requires coordinated movement of the motile cilia of the ependymal epithelium that lines the cerebral ventricles. Here we report that mice lacking the Na(+)/H(+) Exchanger Regulatory Factor 1 (NHERF1/Slc9a3r1, also known as EBP50) develop profound communic...

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Detalles Bibliográficos
Autores principales: Treat, Anny Caceres, Wheeler, David S., Stolz, Donna B., Tsang, Michael, Friedman, Peter A., Romero, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824468/
https://www.ncbi.nlm.nih.gov/pubmed/27055101
http://dx.doi.org/10.1371/journal.pone.0153144