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Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23
AIMS: To investigate the effects and underlying mechanism of dexmedetomidine on the cultured human dendritic cells (DCs). METHODS: Human DCs and cytotoxic T lymphocytes (CTLs) were obtained from human cord blood mononuclear cells by density gradient centrifugation. Cultured DCs were divided into thr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824534/ https://www.ncbi.nlm.nih.gov/pubmed/27054340 http://dx.doi.org/10.1371/journal.pone.0153288 |