Cargando…

Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23

AIMS: To investigate the effects and underlying mechanism of dexmedetomidine on the cultured human dendritic cells (DCs). METHODS: Human DCs and cytotoxic T lymphocytes (CTLs) were obtained from human cord blood mononuclear cells by density gradient centrifugation. Cultured DCs were divided into thr...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Gong, Le, Yuan, Zhou, Lei, Gong, Li, Li, Xiaoxiao, Li, Yunli, Liao, Qin, Duan, Kaiming, Tong, Jianbin, Ouyang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824534/
https://www.ncbi.nlm.nih.gov/pubmed/27054340
http://dx.doi.org/10.1371/journal.pone.0153288