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Dexmedetomidine Inhibits Maturation and Function of Human Cord Blood-Derived Dendritic Cells by Interfering with Synthesis and Secretion of IL-12 and IL-23

AIMS: To investigate the effects and underlying mechanism of dexmedetomidine on the cultured human dendritic cells (DCs). METHODS: Human DCs and cytotoxic T lymphocytes (CTLs) were obtained from human cord blood mononuclear cells by density gradient centrifugation. Cultured DCs were divided into thr...

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Detalles Bibliográficos
Autores principales:	Chen, Gong, Le, Yuan, Zhou, Lei, Gong, Li, Li, Xiaoxiao, Li, Yunli, Liao, Qin, Duan, Kaiming, Tong, Jianbin, Ouyang, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824534/ https://www.ncbi.nlm.nih.gov/pubmed/27054340 http://dx.doi.org/10.1371/journal.pone.0153288

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