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A multi-antigen vaccine in combination with an immunotoxin targeting tumor-associated fibroblast for treating murine melanoma

A therapeutically effective cancer vaccine must generate potent antitumor immune responses and be able to overcome tolerance mechanisms mediated by the progressing tumor itself. Previous studies showed that glycoprotein 100 (gp100), tyrosinase-related protein 1 (TRP1), and tyrosinase-related protein...

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Detalles Bibliográficos
Autores principales: Fang, Jinxu, Hu, Biliang, Li, Si, Zhang, Chupei, Liu, Yarong, Wang, Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824564/
https://www.ncbi.nlm.nih.gov/pubmed/27119119
http://dx.doi.org/10.1038/mto.2016.7