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Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity

Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect of the durable responses observed in some patients and the field is rapidly moving toward immunotherapy. As a further means to engage the immu...

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Detalles Bibliográficos
Autores principales: Bourgeois-Daigneault, Marie-Claude, Roy, Dominic Guy, Falls, Theresa, Twumasi-Boateng, Kwame, St-Germain, Lauren Elizabeth, Marguerie, Monique, Garcia, Vanessa, Selman, Mohammed, Jennings, Victoria Ann, Pettigrew, Jessica, Amos, Sally, Diallo, Jean-Simon, Nelson, Brad, Bell, John Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824565/
https://www.ncbi.nlm.nih.gov/pubmed/27119116
http://dx.doi.org/10.1038/mto.2016.1