A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation

Autophagy dysfunction is implicated in the pathogenesis of Parkinson disease (PD). BECN1/Beclin 1 acts as a critical regulator of autophagy and other cellular processes; yet, little is known about the function and regulation of BECN1 in PD. In this study, we report that dopamine D2 and D3 receptor (...

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Detalles Bibliográficos
Autores principales: Wang, Jian-Da, Cao, Yu-Lan, Li, Qian, Yang, Ya-Ping, Jin, Mengmeng, Chen, Dong, Wang, Fen, Wang, Guang-Hui, Qin, Zheng-Hong, Hu, Li-Fang, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Basic Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824582/
https://www.ncbi.nlm.nih.gov/pubmed/26649942
http://dx.doi.org/10.1080/15548627.2015.1100930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824582/
https://www.ncbi.nlm.nih.gov/pubmed/26649942
http://dx.doi.org/10.1080/15548627.2015.1100930

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