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Transcriptome-scale RNase-footprinting of RNA-protein complexes

Ribosome profiling is widely used to study translation in vivo, but not all sequence reads correspond to ribosome-protected RNA. Here, we develop Rfoot, a computational pipeline that analyzes ribosomal profiling data and identifies native, non-ribosomal RNA-protein complexes in the same sample.. We...

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Detalles Bibliográficos
Autores principales: Ji, Zhe, Song, Ruisheng, Huang, Hailiang, Regev, Aviv, Struhl, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824641/
https://www.ncbi.nlm.nih.gov/pubmed/26900662
http://dx.doi.org/10.1038/nbt.3441