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Transcriptome-scale RNase-footprinting of RNA-protein complexes
Ribosome profiling is widely used to study translation in vivo, but not all sequence reads correspond to ribosome-protected RNA. Here, we develop Rfoot, a computational pipeline that analyzes ribosomal profiling data and identifies native, non-ribosomal RNA-protein complexes in the same sample.. We...
Autores principales: | Ji, Zhe, Song, Ruisheng, Huang, Hailiang, Regev, Aviv, Struhl, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824641/ https://www.ncbi.nlm.nih.gov/pubmed/26900662 http://dx.doi.org/10.1038/nbt.3441 |
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