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Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase

The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is fibromodulin. Its interactions with collagen...

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Detalles Bibliográficos
Autores principales: Kalamajski, Sebastian, Bihan, Dominique, Bonna, Arkadiusz, Rubin, Kristofer, Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825002/
https://www.ncbi.nlm.nih.gov/pubmed/26893379
http://dx.doi.org/10.1074/jbc.M115.693408